Spotlight™ Panels - Symptom-based Panels for Treatable Disorders


Knowing the genetic basis of a patient’s condition is valuable for obtaining a definitive diagnosis, estimating prognosis, determining recurrence risks, and guiding treatment choices. In many cases, the precise genetic diagnosis can be important in therapy selection, particularly when there are known contraindications or recommended treatment options based on genetic results. Courtagen’s Spotlight™ panels provide a targeted approach to genetic testing when apatient’s symptomology is discernable.

Each panel contains between five and 39 genes selected from Courtagen’s larger panels: epiSEEK® Comprehensive Epilepsy and Seizure Disorder panel, nucSEEK® Comprehensive Nuclear Mitochondrial Exome panel, devSEEK® Neurodevelopmental Disorder Panel, and devACT® Clinical Management Panel. Each panel is designed to address a group of disorders with overlapping symptoms, making test selection clear and straightforward.

Available Tests

epiSEEK® Spotlight Panels: Fourteen tests that cover a range of seizure disorders, including Absence Seizures, Aicardi-Goutieres Syndrome, Benign Epilepsies, Brain Malformation Seizures, Early Infantile Epileptic Encephalopathy (EIEE), Fever Sensitive Seizures, Focal Seizures, Infantile Spasms, Joubert Syndrome, Myoclonic A (Progressive), Myoclonic B, Neonatal Seizures, Treatable Seizures A (Medications), and Treatable Seizures B (Other Treatments).

devSEEK® Spotlight Panels: Five tests that target neurodevelopmental disorders, including Noonan Syndrome/RASopathies, Short Stature Disorders, Microcephaly, Lissencephaly, and Holoprosencephaly.

devACT® Spotlight Panels: Five tests that target metabolic disorders, including Congenital Disorders of Glycosylation, Neuronal Ceroid Lipofuscanosis (NCL)/Batten’s Disease, Urea Cyle Disorders, Vanishing White Matter Leukoencephalopathy, and Zellweger Sydrome.

nucSEEK® Spotlight Panels: Two tests for mitochondrial disorders, including Leigh’s Syndrome, and Classical Mitochondrial Disorders.

Product Information Sheets:

Spotlight™ Panels - Symptom-based Panels for Treatable Disorders

Spotlight™ Panels Gene List

Courtagen's Unmatched Customer Support

Turn Around Time: 4-6 weeks. Results are delivered in weeks, not months.

Saliva Sample: DNA for sequencing is reliably extracted from a single saliva sample. No blood draw or muscle biopsy required. (Whole blood and tissue are accepted, as requested.)

Insurance Assistance: Courtagen works with patients, physicians, and insurance carriers to pre-approve each test. Courtagen will bill the insurance company, and is willing to handle an appeal process as needed.

Courtagen Care Financial Assistance Program: Provides financial assistance to patients based on demonstrated financial need. A qualified applicant may be asked to contribute between $0 and a maximum cost sharing of $200 depending on determination of financial need.

Online Portal: A secure physician online portal is available for ordering genetic tests and accessing patient reports when completed.

Genetic Counselors: Available to address physician’s questions regarding Courtagen test results. Contact us at clinical@courtagen.com.

Clinical Experience: Courtagen’s Medical Director, Laboratory Director, and variant science team have over 25 years of experience in the treatment and genetic interpretation of neurological disorders.

Reports: Utilizing Courtagen’s customized Ziphyr® informatics pipeline and thorough clinical evaluation, each report is provided in a concise format with interpretation and recommendations for consideration.

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